Dr. Michael Doyle is the creator of core technologies that underlie such revolutionary products as the Cloud, blockchain/cryptocurrency systems, spatial transcriptomics, and mobile virtual assistants. Dr. Doyle received his PhD from the Department of Cell & Structural Biology at the University of Illinois at Urbana-Champaign (UIUC). He then served as Director of the UIC Biomedical Visualization Laboratory from 1989 to 1993. While on sabbatical at UIUC working with Dr. Paul Lauterbur (2003 Nobel Laureate) on the application of micro-MRI methods to embryo imaging, Dr. Doyle created the Visible Embryo Project (VEP, https://en.wikipedia.org/wiki/Visible_Embryo_Project), a multi-institutional collaboration to create a national online computational and information resource on early human development. In 1994, Dr. Doyle served as Director of the Center for Knowledge Management at the University of California, San Francisco. While at UCSF Medical Center, in 1993, Dr. Doyle led a research team that, while working on the VEP, created fundamental web technologies which enabled Web browsers for the first time to act as platforms for fully interactive embedded applications, in the process pioneering revolutionary Web technologies such as streaming media and cloud computing. To assist the University of California in commercializing the related technology, Dr. Doyle founded Eolas, where he was the architect of the company's research and development efforts, generating over $50 million in royalties for the University of California System. His ‘95 invention of code signing has become the worldwide defacto standard for securing executable Web content. Widely known as the Father of Spatial Biology, his work in high-performance biological computing pioneered that field in 2000. His creation of transient-key cryptography in the late 1990s represented the first decentralized-blockchain system, enabling the later creation of the Bitcoin system, and has been adopted in the x9.95 ANSI National Standard for secure timestamps. And his co-invention of the Skybot intelligent assistant system in 2005 pioneered the mobile AI virtual-assistant product category that is now ubiquitous worldwide.